The CDC National Center for HIV, STD, and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases, and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information.
Lancet (11/20/99) Vol. 354, No. 9192, P. 1782; Ramratnam, Bharat;
Bonhoeffer, Sebastian; Binley, James; et al.
Chronic HIV-1 infection consists of equilibrium between virus
production and clearance. Antiviral therapy disturbs this
balance, however, and decreases the viral load. In an early
report, researchers from the Aaron Diamond AIDS Research Center
in New York report using the removal of plasma by apheresis to
estimate the rate of virion production in individuals chronically
infected with HIV and hepatitis C virus. The results show that
the two viruses are produced and cleared very quickly. The
estimates for HIV-1 clearance are as much as 10 times greater
than previously thought, while clearance rates for hepatitis C
were found to be similar to past estimates.
"U.N. Issues Grim Report on the 11 Million Children Orphaned by
AIDS"
New York Times (12/02/99) P. A10; Altman, Lawrence K.
A United Nations report issued for World AIDS Day shows that over
11 million children have been orphaned by AIDS since 1981, and
that number is expected to reach 13 million by the end of next
year. AIDS is believed to be the leading disease causing
children to lose a parent. Approximately 95 percent of the
orphaned children live in sub-Saharan Africa, UNAIDS and UNICEF
said. The report noted that whereas in the past families would
take care of orphans, "the traditional African extended family is
breaking down under the unprecedented burden of the pandemic."
Dr. Peter Piot, head of UNAIDS, added that many of the orphans
become child laborers or end up on the streets, becoming targets
for gangs, militia, and child armies. In addition, the report
said that, compared to children orphaned for other reasons, AIDS
orphans are at greater risk for malnutrition and related
conditions, illness, abuse, and sexual exploitation.
"Home HIV Test Halted"
USA Today (12/02/99) P. 12D; Hellmich, Nanci
Internet company Medimax Inc. has been charged with falsely
representing the accuracy of its HIV tests. According to the
Federal Trade Commission, the Web site for company founder David
Rothbart claimed Medimax was "the industry leader in the
distribution of clinically proven and FDA-approved diagnostic
rapid tests." Regulators assert, however, that the test on his
site was not approved for sale in the United States. The
agency's complaint hopes to stop Rothbart from further
misrepresentation regarding the tests and also wants him to repay
consumers.
Boston Globe Online (12/02/99) P. A1; Knox, Richard A.
More Americans are being diagnosed with both HIV and hepatitis C
virus (HCV). Injection drug users are at risk for both diseases.
About 40 percent of those with HIV also have HCV, a combination
that makes treatment regimens difficult because of multiple side
effects. Both HIV and hepatitis C can delay symptoms for years,
are unaffected by antibodies, and multiply very quickly. Some
nurses and health workers contract both infections from
accidental needle sticks. Nurse Karen Daley, president of the
Massachusetts Nurses Association, was infected with both viruses
last year after an accidental needle stick. On Wednesday, she
detailed her experience at the Kennedy Library conference,
sponsored by Lemuel Shattuck Hospital, the Massachusetts
Department of Public Health, and the Massachusetts Medical
Society.
New York Times (12/02/99) P. A1; Sanger, David E.
President Clinton spoke against the World Trade Organization's
working secrecy and also condemned the violence of the
demonstrators in Seattle. The protests continued as Clinton
spoke at the port Wednesday. Clinton also announced two
initiatives that will help poor nations in Africa purchase and
distribute anti-AIDS drugs like AZT. A relaxation of American
trade rules will help the countries purchase and distribute the
treatments more cheaply, Clinton said.
Reuters (12/02/99); Page, Jeremy
China has banned its first national condom advertisement two days
after its premiere to mark World AIDS Day. The ad was illegally
promoting sex products, according to the government. The
conservative nature in China and the ban further promote silence
regarding AIDS. Health experts, however, fear the number of HIV
infections from sexual contact will double in two years in China,
indicating the need for such a campaign.
CNN Interactive Online (12/01/99)
AIDS activists have issued their report card on the U.S.
government's response to AIDS, issuing an F for HIV prevention,
an A- for research, and a B for care and treatment. The
activists said that prevention programs have failed to protect
young people being infected with HIV. They also noted the high
cost of AIDS drugs, which many developing nations cannot afford.
The ratings were high in the research, care, and treatment fields
due to ongoing investment in AIDS research and continued funding
in the Ryan White CARE Act. The failing grade for global AIDS
last year was boosted to a C in 1999 after the White House
established a global AIDS initiative.
"Activists Demand AIDS Action"
Boston Globe Online (12/01/99) P. B1; Kong, Dolores
AIDS activists in Massachusetts want the Governor Paul Cellucci
to declare a public health emergency in order to expand needle
exchange programs. The state makes it illegal to have a
hypodermic needle without a prescription, and only four
communities in Massachusetts have used a state law that allows up
to 10 communities to adopt pilot needle exchanges. Public health
statistics show that in places where needle exchanges were
denied--New Bedford, Springfield, and Worcester--over 50 percent
of those with AIDS contracted HIV through intravenous drug
use. In Boston, which has had a needle exchange program for the
past five years, just 29 percent of AIDS patients were exposed to
HIV via intravenous drug use. At a news conference Tuesday,
Governor Cellucci pointed out that several state programs help
battle HIV and AIDS, adding that he is not sure whether a public
health emergency is necessary. Cellucci also noted that the
pilot needle exchange programs require community approval, noting
that "we'll continue to be supportive as long as it's something
the local community wants."
"US Dept. of HHS: HHS Awards $11 Million in HIV/AIDS"
M2 Presswire (12/01/99)
The Health Resources and Services Administration (HRSA) will fund
an $11 million grant program next spring to help four
demonstration projects and one evaluation center to provide
health care to people with HIV/AIDS living on the U.S.-Mexico
border. An increasing number of border dwellers are becoming
infected with HIV, and many have no access to care. The program
is a joint effort between HRSA and its Office of Field
Operations, and is funded mostly by the Ryan White CARE Act.
Business Week (11/15/99) No. 3655, P. 120; Licking, Ellen
About 50 Americans are still infected with HIV each year through
tainted blood transfusions. The tough screening methods for
blood are not perfect, mainly because the antibodies tested for
in blood may not show up for weeks or months in the newly
infected. To make transfusions safer, researchers are studying
three new technologies: nucleic acid testing, blood cleaners for
hepatitis C or syphilis, and a blood filter system. Nucleic acid
testing can detect small amounts of infectious particles in the
bloodstream; however, the filters and nucleic acid tests could
raise the price of blood from $80 to $120 a pint. Although the
risk of contracting HIV or hepatitis C from a blood transfusion
is one in hundreds of thousands, the risks add up as more blood is
given. Nucleic acid testing has shown great promise in catching
hepatitis C in donations. The American Red Cross and American
Blood Centers are using such testing in experimental trials, and
the technique will likely be approved by the Food and Drug
Administration (FDA) in the near future. Meanwhile, Pall Corp.
is developing a filtration system that removes white blood cells,
which can cause infection in blood recipients. Filtered blood
was recommended for use by FDA advisors last year, and the agency
is expected to formally approve the process before the year is
out.